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Predictors of Loss To Follow Up and Mortality Among Children ≤12 Years Receiving Anti Retroviral Therapy during the First Year at a Referral Hospital in Bali

Stefanie Juergens , Anak Agung Sagung Sawitri, Ketut Dewi Kumara Wati, I Wayan Gede Artawan Eka Putra, Tuti Parwati Merati

Stefanie Juergens
Universitas Udayana. Email: nanijuergens@gmail.com

Anak Agung Sagung Sawitri
Universitas Udayana

Ketut Dewi Kumara Wati
Universitas Udayana

I Wayan Gede Artawan Eka Putra
Universitas Udayana

Tuti Parwati Merati
Universitas Udayana
Online First: December 01, 2016 | Cite this Article
Juergens, S., Sawitri, A., Wati, K., Putra, I., Merati, T. 2016. Predictors of Loss To Follow Up and Mortality Among Children ≤12 Years Receiving Anti Retroviral Therapy during the First Year at a Referral Hospital in Bali. Public Health and Preventive Medicine Archive 4(2): 101-106. DOI:10.15562/phpma.v4i2.65


Background and purpose: Many HIV-infected children in Bali have started antiretroviral therapy (ART), but loss to follow up (LTFU) is a continuing concern, and the issue of childhood adherence is more complex compared to adults.

Methods: This was a retrospective study among cohort of 138 HIV+ children on ART in Sanglah General Hospital, Denpasar, Bali from January 2010 to December 2015. Kaplan-Meier analysis was used to describe incidence and median time to LTFU/mortality and Cox Proportional Hazard Model was used to identify predictors. Variables which were analysed were socio-demographic characteristics, birth history, care giver and clinical condition of the children.

Results: Mean age when starting ARV therapy was 3.21 years. About 25% experienced LTFU/death by 9.1 month resulting in an incidence rate of 3.28 per 100 child month. The higher the WHO stage, the higher the risk for LTFU/mortality along with low body weight (AHR=0.90; 95%CI: 0.82-0.99).

Conclusion:  Clinical characteristics were found as predictors for LTFU/mortality among children on ART.

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